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KMID : 1189420030160030145
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Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology
2003 Volume.16 No. 3 p.145 ~ p.163
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The Study on Depigmentation Effects of Aloe, Camellia sinensis and Mel
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Han Eun-Jung
Lee Gil-Young
Kim Hae-Jung
Kim Yoon-Bum
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Abstract
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Objectives : This study was performed to investigate the depigmentation effects of Aloe, Camellia sinensis and Mel.
Methods : Inhibition of tyrosinase activity, melanin production & melanoma cell viability in cultured B16 melanoma cells, UV screen and cytoprotective effects on PC12 cells injured by hydrogen peroxide were measured.
Results : Aloe has some inhibitory effects on tyrosinase activity, on the other hand Camellia sinensis and Mel do not have. They did not show any inhibitory effects on melanin production in melanoma cells and cytoprotective effects on PC12 cells injured by hydrogen peroxide. Aloe and Camellia sinensis have some inhibitory effects on UV screen.
Conclusions : This study shows that Aloe and Camellia sinensis which were generally used for external application have some depigmentation effects. Following this, We should use them for whitening agents and the depigmentation effects of the other natural subjects which were generally used for external application should be examined.
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KEYWORD
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Aloe , Camellia sinensis , Mel , Depigmentation , Tyrosinase , Melanin , UV
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